By Philip M. Parker
In March 2001, the nationwide Institutes of well-being issued the next caution: "The variety of sites providing health-related assets grows each day. Many websites offer invaluable info, whereas others could have info that's unreliable or misleading." in addition, due to the fast bring up in Internet-based details, many hours should be wasted looking, settling on, and printing. on the grounds that in simple terms the smallest fraction of data facing Alexander disorder is listed in se's, corresponding to www.google.com or others, a non-systematic method of web examine could be not just time eating, but in addition incomplete. This e-book was once created for doctors, scholars, and participants of most of the people who are looking to behavior clinical study utilizing the main complex instruments on hand and spending the smallest amount of time doing so.
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Extra info for Alexander Disease - A Bibliography and Dictionary for Physicians, Patients, and Genome Researchers
Therefore, a woman with an X-linked dominant disorder has a 50 percent chance of having an affected daughter or son with each pregnancy. • X-linked recessive inheritance: Because of the difference in sex chromosomes, the probability of passing on an X-linked recessive disorder also differs between men and women. The sons of a man with an X-linked recessive disorder will not be affected, and his daughters will carry one copy of the mutated gene. With each pregnancy, a woman who carries an X-linked recessive disorder has a 50 percent chance of having sons who are affected and a 50 percent chance of having daughters who carry one copy of the mutated gene.
Genetics professionals can help people understand these chances and help them make informed decisions about their health. Factors that Influence the Effects of Particular Genetic Changes Reduced penetrance and variable expressivity are factors that influence the effects of particular genetic changes. These factors usually affect disorders that have an autosomal dominant pattern of inheritance, although they are occasionally seen in disorders with an autosomal recessive inheritance pattern. Reduced Penetrance Penetrance refers to the proportion of people with a particular genetic change (such as a mutation in a specific gene) who exhibit signs and symptoms of a genetic disorder.
Males are more frequently affected than females, and the chance of passing on the disorder differs between men and women. Families with an X-linked recessive disorder often have affected males, but rarely affected females, in each generation. A striking characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons (no male-to-male transmission). hemophilia, Fabry disease Codominant In codominant inheritance, two different versions (alleles) of a gene can be expressed, and each version makes a slightly different protein.